AO2 Clear 30 Day Supply + 10 Travel Packs
$72.99 — or subscribe to save 20%
Be ready wherever you go with the A02 Clear Combo. 30-Day Supply + 10 Travel Packs.
I had horrible hormonal acne all over my cheeks when I started Ao2 clear. A lot of other reviewers saw results immediately. Though the treatment helped calm my skin down, I was not breakout-free until week 5. I am only getting small bumps from time to time now. No cysts! Stick with it if your acne is really bad, it will help! I am so thankful for Ao2 clear. Acne was wrecking my confidence and I refuse to get on Accutane. I hope it is sold in stores soon!
— Reese (verified A02 Clear user).
In stock
Shipping is currently available to the US, Canada, Europe and Australia! If you don’t see your country, please get in touch with us.
Two flawless ingredients are all you need

Distilled Water

Oxygen Nanobubbles
AO2 Clear Results - 2x daily for 30 days & get clear!
"Before AO2 Clear, I tried every OTC and prescription treatment available and nothing ever fully cleared my skin. I was part of a clinical trial for a new laser therapeutic that I was also a non-responder for. I tried AO2 Clear after seeing Dr. Gendler post about it and I wasn’t sure if it would actually work, but I’m getting married in a few months and had nothing to lose from trying something new. I saw a reduction in my acne in only 2 weeks, with my skin becoming 100% acne-free in only 8 weeks. This product really gave me part of my life back after over a decade of nothing working. I tell literally everyone I know about this product!!!"
AO2 Clear Results - 2x daily for 30 days & get clear!
"Before AO2 Clear, I tried every OTC and prescription treatment available and nothing ever fully cleared my skin. I was part of a clinical trial for a new laser therapeutic that I was also a non-responder for. I tried AO2 Clear after seeing Dr. Gendler post about it and I wasn’t sure if it would actually work, but I’m getting married in a few months and had nothing to lose from trying something new. I saw a reduction in my acne in only 2 weeks, with my skin becoming 100% acne-free in only 8 weeks. This product really gave me part of my life back after over a decade of nothing working. I tell literally everyone I know about this product!!!"
Breakthrough skin science
Acne is caused by anaerobic bacteria that thrive in places with a critical lack of oxygen, e.g., your pores. Using revolutionary nanobubble technology, AO2 CLEAR delivers 100% pure oxygen deep into your pores to kill the inflammation-causing bacteria on contact. Our patented technology delivers more oxygen than any other treatment for unprecedented soothing and preventative results.
WHICH AO2 SKIN PRODUCT IS RIGHT FOR YOU
AO2 Clear’s potency is in the packaging
To preserve nanobubble suspension even further, take care to replace the cap and close it quickly and tightly immediately after pouring, every use. This will minimize the amount of air that enters the pouch and maximize AO2 CLEAR’s strength by preserving oxygenation from pouch start to finish.
AO2 CLEAR's potency is in the packaging
Your 30-day supply of AO2 CLEAR comes with four 150 ml pouches of solution, each one holding billions of oxygen nanobubbles. Our nanobubbles have a naturally occurring stability that helps keep them suspended and ready for action, and our pouches have been custom developed to enhance that stability.
To preserve nanobubble suspension even further, take care to replace the cap and close it quickly and tightly immediately after pouring, every use. This will minimize the amount of air that enters the pouch and maximize AO2 CLEAR’s strength by preserving oxygenation from pouch start to finish.
"I saw a reduction in my acne in only 2 weeks, with my skin becoming 100% acne-free in only 8 weeks. This product really gave me part of my life back after over a decade of nothing working. I tell literally everyone I know about this product!!!”
Paige
“I enjoy using AO2 considering that my skin got very dry from acne treatments, and I wanted something that is good for acne without harsh chemicals and over-drying.”
Alexandra
"AO2 Clear truly gave me my confidence back! After struggling with hormonal acne, eczema and the most sensitive skin, I was skeptical, but it exceeded all expectations. I will never not use this in my routine. I 1000% recommend!"
madeline
"Hands down one of the best acne/compromised skin products that I’ve used in a very long time. Works immediately to tackle the problem."
Eva Simmons - O'Brien., MD
FAQs
Where do you ship?
Is AO2 Clear safe for everyone?
What results can I expect to see on my skin?
How do I use AO2 CLEAR?
1. Place a fresh new sponge in the tray (Do not reuse sponges—used sponges can collect and breed bacteria)
2. Dispense AO2 CLEAR solution onto the sponge until fully saturated (a drippy sponge delivers the best results)
3. Apply liberally to your entire face—for sensitive skin or active breakouts, dab the product onto your skin rather than scrubbing to avoid potential irritation
4. Let your skin air dry until it’s almost dry, then apply your next product while it’s still slightly damp—do not pat dry
5. Apply any additional products from your existing skincare routine, such as moisturizer or sunscreen
NOTE: Each pouch contains 15 applications and is meant to be used twice a day. Discard each pouch 14 days after opening—even if there’s liquid left, switching to a fresh pouch ensures you’re getting the most effective product.
Do I have to give up my existing skin care routine to use AO2 Clear?
What side effects are associated with AO2 Clear?
How often should I use AO2 Clear?
Use AO2 CLEAR twice daily—once in the morning and once at night—on clean, dry skin. It should be the first step after cleansing and before applying serums, moisturizers, or SPF. AO₂ CLEAR easily fits into any skincare routine without requiring you to change anything else.
Each 30-day kit comes with four pouches, and each pouch contains 15 applications (used twice a day). Once opened, a pouch is most effective when used within 14 days, so we recommend replacing the cap tightly after each use to keep the oxygen nanobubbles potent.
With consistent use, most people start to see real improvements in 2 to 4 weeks—think clearer, calmer, and more hydrated skin.
How long before I see results?
Can I reuse sponges? What about the tray?
Your sponge is also compostable so you don’t need to worry about filling up the landfill. Toss them in your compost or the trash as they will biodegrade.
For the tray, you can reuse it. We recommend you wash the trays with soap and water and store them in a drawer or cabinet. Because they are not as porous as the sponges, a quick clean between uses will minimize any bacterial growth.
Can I use other acne treatments while using AO2 Clear?
What is the shelf life of AO2 Clear?
Once you open your A02 CLEAR pouch, it has a maximum efficacy of 14 days. It can be stored in your bathroom or the refrigerator depending on your preference.
Each pouch contains 15 applications. We recommend you use AO2 CLEAR twice daily for 3o consecutive days for maximum benefit. Also remember to use a fresh clean sponge with each applications.
Do you recommend any different usage based on skin type or acne severity?
Do I have to use the provided sponges for application?
The sponges have also been designed to give you gentle exfoliation that can help clear your pores of dead skin cells and make way for our oxygen nanobubbles to get to work. If you notice any persistent redness or irritation it is likely that your skin needs less exfoliation and we recommend switching to a cotton round or fine gauze instead.

