Menopausal Skin Needs Special Care—AO2 Clear Delivers It

Safe. Effective. Backed by Science.

Breakouts don’t always end in your teenage years. During menopause, hormonal shifts can lead to unexpected acne, increased sensitivity, and changes in skin texture. AO2 Clear’s oxygen-powered formula is designed to calm inflammation, restore balance, and support your skin through every stage of life.

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See Why Skincare Experts & Women Trust AO2 Clear

Watch board-certified dermatologists & real users share their experiences.

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Why Does Menopause Trigger Acne?

As estrogen levels decline, androgen hormones (like testosterone) become more dominant, increasing oil production and leading to clogged pores and breakouts. At the same time, the skin’s natural ability to renew and repair slows down, making acne and irritation more stubborn.

Menopausal skin experiences

Increased oil production due to hormone imbalance

As estrogen decreases, excess oil production can clog pores and contribute to adult breakouts.

Reduced Collagen & Elasticity

Lower collagen levels cause the skin to thin, making it more fragile and prone to fine lines, wrinkles, and irritation.

Slower Cell Turnover & Stubborn Breakouts

With age, the skin takes longer to shed dead cells, leading to clogged pores, prolonged acne, and lingering dark spots.

Heightened Sensitivity & A Compromised Skin Barrier

Menopausal skin tends to be more reactive, experiencing increased dryness, redness, and inflammation.

AO2 Clear helps rebalance and restore menopausal skin—without irritation or harsh chemicals.

How AO2 Clear Supports Menopausal Skin

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Floods pores with oxygen to eliminate acne-causing bacteria

Menopausal acne is often triggered by excess oil and slower skin renewal. AO2 Clear’s oxygen nanobubbles create an oxygen-rich environment where acne-causing bacteria can’t survive—helping to prevent and clear breakouts without irritation or dryness.

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Calms Redness & Strengthens Sensitive Skin

Hormonal changes can make menopausal skin more reactive, leading to redness, irritation, and inflammation. AO2 Clear delivers pure oxygen, helping to soothe sensitivity and strengthen the skin barrier over time.

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Speeds Up Healing & Skin Renewal

As cell turnover slows with age, blemishes take longer to heal. AO2 Clear helps remove dead skin cells and accelerates healing, promoting a smoother, more even complexion.

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Boosts Collagen for Firmer, Healthier Skin

Declining estrogen leads to collagen loss, making skin thinner and more fragile. Oxygen plays a vital role in collagen synthesis, helping to maintain firmness, elasticity, and overall skin strength.

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Hydrates & Balances Without Clogging Pores

Unlike harsh acne treatments that strip moisture and trigger excess oil production, AO2 Clear hydrates while keeping skin balanced—allowing it to absorb skincare products more effectively.

WHAT DERMATOLOGISTS SAY

“AO2 Clear is an ideal solution for acne during menopause. It’s completely safe, as it contains only oxygen and water. Additionally, AO2 Clear has no potential to irritate the skin during this period when the skin may be unusually reactive to skincare products.”

— Valerie Hanft, MD, Board-Certified Dermatologist

real people, real results

real people,

real results

"I saw a reduction in my acne in only 2 weeks, with my skin becoming 100% acne-free in only 8 weeks. This product really gave me part of my life back after over a decade of nothing working. I tell literally everyone I know about this product!!!”

Paige

“I enjoy using AO2 considering that my skin got very dry from acne treatments, and I wanted something that is good for acne without harsh chemicals and over-drying.”

Alexandra

"AO2 Clear truly gave me my confidence back! After struggling with hormonal acne, eczema and the most sensitive skin, I was skeptical, but it exceeded all expectations. I will never not use this in my routine. I 1000% recommend!"

madeline

FAQs

Where do you ship?

We currently ship to the United States, Canada, United Kingdom, Ireland, France, Germany and Australia. If your country isn’t listed, we’re constantly exploring opportunities to expand our reach! Stay tuned for updates or contact our support team for more information.

Is AO2 Clear safe for everyone?

Yes. AO2 Clear is completely safe for all people and all skin types. It’s even safe to use while pregnant, nursing or trying to conceive.

What results can I expect to see on my skin?

With consistent use your skin should be clearer, more hydrated, evenly textured, brighter, and overall healthier and better nourished. You should not experience the drying or irritation that accompanies many traditional acne products like Retin-A.

Do I have to give up my existing skin care routine to use AO2 Clear?

Nope! Because AO2 Clear is a unique and hyper clean product it fits right into your existing routine, whether that’s cleanse and go a multi-step regimen. Start with your favorite cleanser, then apply AO2 Clear and allow the solution to air dry. Don’t be afraid of a few drips, it will dry quickly and your face won’t be wet long. After that you can apply whatever creams or serums you like. 

What side effects are associated with AO2 Clear?

Because AO2 Clear is only oxygen and distilled water, there is no potential for irritation or other adverse reactions.

How often should I use AO2 Clear?

We recommend using it twice daily after washing and drying your face with a mild cleanser. Place your sponge into the tray and then squeeze the A02 Clear pouch saturating the sponge.  Each pouch is measured to provide 30 applications, twice daily for 15 days.

How long before I see results?

If using AO2 Clear consistently twice daily, you should start to see improvement within the first two weeks. Because oxygen acts as a natural antibacterial against the specific bacteria that causes acne inflammation the preventative benefits act cumulatively—the longer you use the product, the more benefit you can expect to see—clarity, hydration, and even texture.

Can I reuse sponges? What about the tray?

We recommend you use a fresh new sponge with each application. A previously used sponge can harbor bacteria (either removed from your skin during the AO2 application or aerosolized in the bathroom). If you reuse the same sponge later you are risking adding bacteria back to your skin surface.

Your sponge is also compostable so you don’t need to worry about filling up the landfill.  Toss them in your compost or the trash as they will biodegrade.

For the tray, you can reuse it. We recommend you wash the trays with soap and water and store them in a drawer or cabinet. Because they are not as porous as the sponges, a quick clean between uses will minimize any bacterial growth.

Can I use other acne treatments while using AO2 Clear?

Because AO2 Clear’s hyper clean formula consists of just distilled water and oxygen nanobubbles that clear and hydrate your skin you can use it in conjunction with other treatments. But, many of our study participants and customers found it unnecessary to continue their other treatments because of how effective and gentle AO2 Clear is on their skin. For advice on any prescription medication changes, please contact your medical or healthcare provider.

What is the shelf life of AO2 Clear?

AO2 Clear has a shelf life of 1 year if unopened and stored in a cool place. You will see the manufacturing date of your A02 on the back of each pouch on the bottom.

Once you open your A02 Clear pouch, it has a maximum efficacy of 20 days. It can be stored in your bathroom or the refrigerator depending on your preference. 

Each pouch contains 30 applications. We recommend you use AO2 Clear twice daily for 3o consecutive days for maximum benefit.  Also remember to use a fresh clean sponge with each applications.  

Do you recommend any different usage based on skin type or acne severity?

We find that people with sensitive skin or severe or very inflamed acne should apply using light pressure so as not to irritate your skin with the sponge texture. Those who don’t have sensitive skin and/or have a lot of blackheads and whiteheads can press more firmly for more exfoliation. For your personal medical concerns please seek the advice of your medical or healthcare provider.

Do I have to use the provided sponges for application?

The sponges are sized to hold the correct amount of AO2 Clear for each application making it easy to administer an equal amount twice daily for two weeks. 

The sponges have also been designed to give you gentle exfoliation that can help clear your pores of dead skin cells and make way for our oxygen nanobubbles to get to work. If you notice any persistent redness or irritation it is likely that your skin needs less exfoliation and we recommend switching to a cotton round or fine gauze instead.

How is AO2 Clear different from other products that deliver oxygen to the skin?

AO2 Clear is the only topical acne treatment that contains just oxygen and distilled water. It’s also the only product to harness nanobubble technology for such an extraordinarily high gradient of oxygen pressure. No other product is as clean and powerful.

What if I forget to put the cap back on the pouch?

Closing the cap quickly and tightly is a critical step in ensuring maximum product effectiveness for the duration of each two week pouch. If left open the nanobubbles will begin to rise to the surface and pop, decreasing oxygen concentration in the solution. Without a high oxygen concentration AO2 Clear will not work as well, so please close quickly and tightly. 

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