PATENTED OXYGEN NANOBUBBLE SKINCARE

Acne bacteria live where your cleanser
can’t reach.

AO2 CLEAR® sends billions of oxygen nanobubbles 1,000× smaller than a pore, straight to the anaerobic bacteria that cause breakouts. Made with only 2 ingredients.

(173 customer reviews)

SOUND FAMILIAR?

01    Differin
02   Proactiv
03   Benzoyl peroxide
04   Salicylic acid cleansers
05   The $80 vitamin C serum
06   Prescription antibiotics

They either didn’t work, or they worked by waging war on your skin. Dryness. Peeling. Irriation. Then more breakouts.

The reason nothing fully worked? Most products treat the symptom. Almost none reach the cause.

Acne lives where oxygen can’t reach. We change that.

C. acnes bacteria, that cause acne, thrive in oxygen-deprived pores. AO2 delivers high-pressure oxygen nanobubbles that are 1,000× smaller than a pore, allowing them to penetrate deep into your skin. As these nanobubbles move from a high-pressure state into the skin’s lower-pressure environment, they flood your pores with oxygen stopping the growth of the C. acnes bacteria and supporting clearer, healthier-looking skin.

TRADITIONAL SKINCARE

30-ingredient formulas. Surface-level.

 

    • Ingredient labels you can’t pronounce
    • Sit on top of the skin, never reach the source
    • Results that fade the moment you stop
    • Acids, retinols, antibiotics that strip the barrier
AO2 SKIN

Two ingredients. Sub-pore. Proven.

 

    • Just water + oxygen nanobubbles
    • 1,000× smaller than a pore, reaches where breakouts begin
    • Eliminates anaerobic acne bacteria on contact
    • Calms the skin barrier instead of stripping it

Acne lives where oxygen can’t reach. We change that.

C. acnes bacteria, that cause acne, thrive in oxygen-deprived pores. AO2 delivers high-pressure oxygen nanobubbles that are 1,000× smaller than a pore, allowing them to penetrate deep into your skin. As these nanobubbles move from a high-pressure state into the skin’s lower-pressure environment, they flood your pores with oxygen stopping the growth of the C. acnes bacteria and supporting clearer, healthier-looking skin.

★★★★★

“I tried every prescription, every cleanser, every $80 serum. AO2 CLEAR is the only thing that worked. My skin is completely clear for the first time since I was 14.”

Paige H.   ·   A decade of failed treatments   ·   Cleared in 8 weeks

TRADITIONAL SKINCARE

30-ingredient formulas. Surface-level.

 

    • Ingredient labels you can’t pronounce
    • Sit on top of the skin, never reach the source
    • Results that fade the moment you stop
    • Acids, retinols, antibiotics that strip the barrier
AO2 SKIN

Two ingredients. Sub-pore. Proven.

 

    • Just water + oxygen nanobubbles
    • 1,000× smaller than a pore, reaches where breakouts begin
    • Eliminates anaerobic acne bacteria on contact
    • Calms the skin barrier instead of stripping it

What happens when you stop fighting your skin.

★★★★★

“I tried every prescription, every cleanser, every $80 serum. AO2 CLEAR is the only thing that worked. My skin is completely clear for the first time since I was 14.”

Paige H.   ·   A decade of failed treatments   ·   Cleared in 8 weeks

★★★★★

“AO2 Clear truly gave me my confidence back! After struggling with hormonal acne, eczema and the most sensitive skin, I was skeptical, but it exceeded all expectations. I will never not use this in my routine!”

Madeline M.   ·   Hormonal acne   ·   Cleared in 2 weeks

★★★★★

“I enjoy using AO2 considering that my skin got very dry from acne treatments, and I wanted something that is good for acne without harsh chemicals and over-drying.”

Alexandra   ·   Cystic acne   ·   Progress after 3 weeks

CLINICAL STUDY RESULTS

88% improved. In 30 days.

88%

 

of patients reported improvement
after 30 days of twice-daily use

35%

 

described results as dramatic

of the 88% who reported improvement

86%

loved using AO2 CLEAR

and were satisfied with their experience

77%

 

would reccommend AO2 CLEAR

to a friend or family member

★★★★★

“AO2 is the most interesting innovation I’ve seen in acne care in 20 years. The mechanism is sound, the safety profile is exceptional, and the results in my practice match the clinical data.”
EVA SIMMONS-O’BRIEN, MD · BOARD-CERTIFIED DERMATOLOGIST

CLINICAL STUDY RESULTS

88% improved.
In 30 days.

88%

 

of patients reported improvement

after 30 days of twice-daily use

35%

 

described results as dramatic

of the 88% who reported improvement

86%

 

loved using AO2 CLEAR

and were satisfied with their experience

77%

 

would reccommend AO2 CLEAR

to a friend or family member

★★★★★

“AO2 is the most interesting innovation I’ve seen in acne care in 20 years. The mechanism is sound, the safety profile is exceptional, and the results in my practice match the clinical data.”

EVA SIMMONS-O’BRIEN, MD
BOARD-CERTIFIED DERMATOLOGIST

HOW TO USE

Fit AO2 into the routine you already have.

No overhaul required.
Add AO2 CLEAR® after cleansing, everything
else stays the same.

01

 

Cleanse

Use your usual gentle cleanser. Pat dry with a clean towel.

02

 

Apply

Pour solution into the tray until halfway full. Apply generously over your face with the sponge.

03

 

Air dry

Let your skin dry naturally. Don’t touch your face or apply other products until fully dry.

04

 

Continue

Follow with moisturizer, sunscreen, or other products as usual. Nothing changes.

EACH 30 DAY KIT INCLUDES 4 POUCHES AND SPONGES
APPLY TWICE DAILY · 15 APPLICATIONS PER POUCH
RESULTS WITHIN 2-4 WEEKS OF CONSISTENT USE

Shop AO2 CLEAR

AO2 CLEAR delivers billions of oxygen nanobubbles, each 1000x smaller than the diameter of a single pore, directly into your skin. No harsh chemicals. No long ingredient list. Just oxygen and distilled water, working at a level traditional skincare can’t reach.

Which skin situation sounds like you?

AO2 works for almost every skin type, but we’ve built specific guidance for your situation.

FOR

Teen Acne

 

FOR

Pregnancy-Safe

 

FOR

Hormonal Skin

 

FOR

Sensitive Skin

 

FOR

Post-Procedure

 

FOR

Menopause Skin

 

PRO PARTNERS

Skincare Professionals

 

Zvi Yaniv, PhD

Zvi Yaniv, PhD

Chief Science Officer » Physicist » Inventor

A physicist with a
problem.
An idea that
changed skincare.

Dr. Zvi Yaniv, a physicist with decades of nanotechnology experience and over 300 patents to his name, developed peripheral neuropathy. He couldn’t get oxygen to his nerve endings.

When existing treatments failed to solve the problem, he developed a new delivery mechanism: oxygen nanobubbles suspended within a topical gel. This relieved his symptoms where traditional approaches could not.

Building on Dr. Yaniv’s breakthrough, our team recognized that this same technology could help accomplish something the skincare industry had long struggled to achieve, delivering oxygen below the skin’s surface to reach areas conventional skincare products simply cannot.

Fair questions. Straight answers.

Is AO2 CLEAR safe for everyone?

Yes. AO2 CLEAR is completely safe for all people and all skin types. It’s even safe to use while pregnant, nursing or trying to conceive.

What results can I expect to see on my skin?

With consistent use your skin should be clearer, more hydrated, evenly textured, brighter, and overall healthier and better nourished. You should not experience the drying or irritation that accompanies many traditional acne products like Retin-A.

What side effects are associated with AO2 CLEAR?

Because AO2 CLEAR is made with only oxygen and distilled water, there is no potential for irritation or other adverse reactions with either product.

How often should I use AO2 CLEAR?

We recommend using AO2 CLEAR twice daily after washing and drying your face with a mild cleanser. Each pouch is measured to provide 15 applications, twice daily for a week.

How long before I see results?

If using AO2 CLEAR consistently twice daily, you should start to see improvement within the first two weeks. Because oxygen acts as a natural antibacterial against the specific bacteria that causes acne inflammation the preventative benefits act cumulatively. The longer you use the product, the more benefit you can expect to see clarity, hydration, and even texture.

Do I have to give up my existing skin care routine to use AO2 CLEAR?

Nope! Because both AO2 CLEAR is a unique and hyper clean product they fit right into your existing routine, whether that’s cleanse and go a multi-step regimen. Start with your favorite cleanser, then apply AO2 CLEAR,  and allow the solution to air dry. Make sure your sponge is fully saturated and drippy, it will dry quickly and your face won’t be wet long. After that you can apply whatever creams or serums you like. 

Can I use other acne treatments while using AO2 CLEAR?

Because AO2 CLEAR’s hyper clean formula consists of just distilled water and oxygen nanobubbles that clear and hydrate your skin you can use it in conjunction with other treatments. But, many of our study participants and customers found it unnecessary to continue their other treatments because of how effective and gentle AO2 CLEAR is on their skin. For advice on any prescription medication changes, please contact your medical or healthcare provider.

Do you recommend any different usage based on skin type or acne severity?

We find that people with sensitive skin or severe or very inflamed acne should apply using light pressure so as not to irritate your skin with the sponge texture. Those who don’t have sensitive skin and/or have a lot of blackheads and whiteheads can press more firmly for more exfoliation. For your personal medical concerns please seek the advice of your medical or healthcare provider.

How is AO2 CLEAR different from other products that deliver oxygen to the skin?

AO2 CLEAR is the only product to harness nanobubble technology for such an extraordinarily high gradient of oxygen pressure. No other product is as clean and powerful.

How exactly does the nanobubble gradient work?

The transfer of a gas like oxygen from one location to another depends on the difference, or gradient, in concentration between the two locations. If that gradient is significant, oxygen will move from the high-concentration one to the low-concentration one. In our case, the two locations are the skin surface and the skin pores. A good example of an oxygen gradient is hyperbaric oxygen therapy. This treatment is costly, cumbersome, and has the potential for serious side effects. AO2 uses the same principle of an oxygen gradient as hyperbaric therapy, but it’s convenient, low cost, and has no potential side effects.

How do we know what is better between oxygen, hydrogen or ozone?

Oxygen is critical in promoting healthy skin by supporting cell regeneration and collagen production. It helps enhance skin elasticity, reduce the appearance of fine lines and wrinkles, and contributes to a radiant complexion. Additionally, oxygen can assist in healing wounds and combating bacteria, promoting an overall rejuvenated and refreshed skin appearance.

Hydrogen, although it has some antioxidant properties, doesn’t play as central a role in these essential functions for skin. While ozone has some antioxidant and antimicrobial benefits, its use in skincare is debated due to concerns about potential side effects and limited scientific evidence. Oxygen is generally considered safer and more widely accepted for skincare, offering proven advantages without the uncertainties associated with hydrogen and ozone.

Real Customers. Real Results.

173 reviews for AO2 Clear

4.8
Based on 173 reviews
5 star
93
93%
4 star
0
0%
3 star
1
1%
2 star
2
2%
1 star
2
2%

Customer Images

Image #1 from Shelly Edgin
Image #1 from Anya
Image #1 from Isabella M
Image #2 from Isabella M
Image #1 from Allegra
Image #1 from Ashley Iovinelli
Image #2 from Ashley Iovinelli
Image #1 from Madison Gerber
Image #2 from Madison Gerber
Image #1 from Bridget McCann
Image #1 from Shelly Edgin

Shelly Edgin

My 18 year old athletic son asked me to reorder AO2 asap when he ran out of product. He said it clears his acne and keeps his skin healthy even after shaving. We did expedited shipping and his face is on the mend again. We believe in this product and see results fast. I decided to order product for me to improve menopause skin and scars. Going on a second week using AO2 my skin feels soft, hydrated, and watching for improvement with scaring. I am impressed with results.

(1) (0)
Image #1 from Anya

Anya

I recently added AO2 CLEAR to my skincare routine and I absolutely love it! I use it as a toner, right after washing my face and it feels sooo refreshing! I also love using it right after exfoliating my face to help repair the skin barrier. After using AO2 CLEAR, I noticed my skin appears brighter and softer! Love that this product is truly CLEAN, with 100% natural ingredients (water & oxygen). Highly recommend!

(0) (0)
Image #1 from Isabella M

Isabella M

I hope you can appreciate the evolution in very real skin! I decided to give AO2 clear a chance because I got pregnant and had to stop doing laser in my face and what was peach fuzz with the hormones became too thick so I couldn’t just ignore it! I had to start epilating but every time I did it I would get a breakout, it was itchy and I started getting hyperpigmentation and scarring. Since I went all natural with pregnancy there was not much I could do until I found this product. It’s been like 3-4 months of using AO2 clear and this is the progress using pretty much only this and moisturizer, I don’t use anything else for the hyperpigmentation. I still get hormonal acne here and there, and to be fair my diet has not been the best but my skin is actually healing! I can epilate as much as I want and I don’t get any new breakouts, it’s not itchy anymore, my skin is less congested in general and my scars are slowly fading. I even got the back and chest hormonal acne under control just passing the pad on those areas after using it on my face. I’m never stopping using this stuff.

(1) (0)
Image #2 from Isabella M

Isabella M

I hope you can appreciate the evolution in very real skin! I decided to give AO2 clear a chance because I got pregnant and had to stop doing laser in my face and what was peach fuzz with the hormones became too thick so I couldn’t just ignore it! I had to start epilating but every time I did it I would get a breakout, it was itchy and I started getting hyperpigmentation and scarring. Since I went all natural with pregnancy there was not much I could do until I found this product. It’s been like 3-4 months of using AO2 clear and this is the progress using pretty much only this and moisturizer, I don’t use anything else for the hyperpigmentation. I still get hormonal acne here and there, and to be fair my diet has not been the best but my skin is actually healing! I can epilate as much as I want and I don’t get any new breakouts, it’s not itchy anymore, my skin is less congested in general and my scars are slowly fading. I even got the back and chest hormonal acne under control just passing the pad on those areas after using it on my face. I’m never stopping using this stuff.

(1) (0)
Image #1 from Allegra

Allegra

This product is absolutely amazing! Not only have I noticed a clearer complexion but it leaves skin hydrating! I use it morning and night. I also use it after a workout for some extra cleaning until I’m actually able to wash my face and neck. I need to restock actually!

(1) (0)
Image #1 from Ashley Iovinelli

Ashley Iovinelli

AO2 Clear has been the best addition to my skincare routine! I won’t use sink water on my face, I’ve tested the water, so I know the contaminants in it and after years of cystic acne, eczema and reoccurring facial shingles I can’t bring myself to put that junk on my face. The AO2 Clear face water is the perfect clean and supportive cleansing I need at the end of the day to help refresh my skin. I had already done a lot to heal internally and this was the topical skin product I’ve been waiting for. My skin microbiome has healed so much, I rarely get cysts anymore and I’ve been able to simplify my skincare regimen 🙂

(0) (0)
Image #2 from Ashley Iovinelli

Ashley Iovinelli

AO2 Clear has been the best addition to my skincare routine! I won’t use sink water on my face, I’ve tested the water, so I know the contaminants in it and after years of cystic acne, eczema and reoccurring facial shingles I can’t bring myself to put that junk on my face. The AO2 Clear face water is the perfect clean and supportive cleansing I need at the end of the day to help refresh my skin. I had already done a lot to heal internally and this was the topical skin product I’ve been waiting for. My skin microbiome has healed so much, I rarely get cysts anymore and I’ve been able to simplify my skincare regimen 🙂

(0) (0)
Image #1 from Madison Gerber

Madison Gerber

I have been using A02 clear since 2024 and it has totally transformed my skin!!! I love that it’s literally water and I can feel confident about the ingredients I’m putting on my face. I’m so grateful I can accredit my clear skin to this amazing company!!😍😍😍

(0) (0)
Image #2 from Madison Gerber

Madison Gerber

I have been using A02 clear since 2024 and it has totally transformed my skin!!! I love that it’s literally water and I can feel confident about the ingredients I’m putting on my face. I’m so grateful I can accredit my clear skin to this amazing company!!😍😍😍

(0) (0)
Image #1 from Bridget McCann

Bridget McCann

This stuff is LIFE CHANGING. This is coming from someone who battled cystic acne for years. My skin was in a much better place but still struggling. Just look at the difference a month with AO2 Clear made!! Will never be without it.

(0) (0)
Image #1 from Shelly Edgin
Image #1 from Anya
Image #1 from Isabella M
Image #2 from Isabella M
Image #1 from Allegra
Image #1 from Ashley Iovinelli
Image #2 from Ashley Iovinelli
Image #1 from Madison Gerber
Image #2 from Madison Gerber
Image #1 from Bridget McCann
1-5 of 173 reviews
  1. My 18 year old athletic son asked me to reorder AO2 asap when he ran out of product. He said it clears his acne and keeps his skin healthy even after shaving. We did expedited shipping and his face is on the mend again. We believe in this product and see results fast. I decided to order product for me to improve menopause skin and scars. Going on a second week using AO2 my skin feels soft, hydrated, and watching for improvement with scaring. I am
    impressed with results.

    Image #1 from Shelly Edgin
    (1) (0)
  2. I am loving AO2, and have only been using it for a few days! I am in menopause and have blackheads and rosacea that I could never seem to get rid of or get under control! I was introduced to this product by some ladies in my neighborhood, and it has given me such confidence with my face!

    (0) (0)
  3. Love A02! Always clears up my skin quickly and the bubbles getting absorbed into your skin every morning is such a refreshing way to start the day!

    (2) (0)
  4. Excited to start my good skin journey.

    (0) (0)
  5. I have been using AO2 clear for about a year now. My skin is sensitive to scents and harsh ingredients. I have found that AO2 leaves my skin feeling fresh and clean without irritating my skin. I used to get redness and irritated rated skin, but using this 2 times a day has helped to calm my skin. Both the regular and new hydrate work well with my sensitive skin. The pads that come with the bags are fantastic.

    (1) (0)
Add a review
You must be logged in to post a review Log In

Ready to try acne support without
harsh actives?

Start with AO2 CLEAR and give your skin a simpler, calmer routine built around oxygen nanobubble technology.